If the study requires kit reconciliation and the site is drug destruction capable, you must mark the kits as ready for destruction. This procedure also applies to rollover studies.

1. Access the Site Inventory tab
2. From the Site drop-down, select a site.
3. Use the Status drop-down to filter the view so you see only the kits that are ready for destruction. For example, you might select all statuses except Available, Dispensed, In Transit, and Missing, though you might select Available if the site is shut down.
   For more information, see Filter kits in a site's inventory.
4. Select the kits that are ready for destruction.
5. On the Inventory Management side panel, click Update Kits.
6. From the Kit Status drop-down, select Pending Destruction.
7. Enter the number of Total Returned Units and Total Missing Units in the fields.

   Note:

   If you cannot see these fields, reach out to your clinical supply manager and make sure Kit Reconciliation is set as required when you Specify supply settings.
8. Enter a Reason For Change in the text box.
9. Depending on your study configuration, click the available option to update
   • Update & Open Form: This option is available when a drug reconciliation form exists and the current site is drug-destruction capable. Clicking this updates the kits status and opens the drug reconciliation form for you to complete it. See Complete a drug reconciliation form.

     Next step for a drug-destruction facility would be to destroy kits and Mark kits as destroyed.

   • Update & Ship Kits: This option is available for sites that are not drug-destruction capable. Clicking this updates the kits and generates the shipment.

     For the next step you are redirected to the shipments page to Complete a drug reconciliation form for kits already sent for destruction (if applicable) and Ship kits to a drug destruction depot.

   If the depot that sent the kits to the site is drug destruction capable, the kits are sent back to that depot.

   If the depot that sent the kits isn't drug destruction capable, the kits are sent to the depot that is marked as a drug destruction facility and that is associated with the country that the site is in.

   If multiple drug-destruction depots ship kits to a site, you can choose the destination depot. From the Send Option drop-down, select either:

   • Send back to a supply depot
   • Send to a destruction facility and select the destruction facility from the drop-down.

   Shipments are created based on the temperature requirements for the kits. For example, if you mark a refrigerated kit and a frozen kit as Pending Destruction, one shipment is created for the refrigerated kit, and another shipment is created for the frozen kit. If the return shipments don't have temperature requirements, consider combining multiple packing lists in one shipment.